Product Overview
PRIMLEV 2.5mg/300mg is a prescription opioid analgesic designed for the management of mild to moderate pain in patients who require an opioid-based medication but benefit from a lower-strength dose. Each tablet contains a precise balance of oxycodone hydrochloride (an opioid) and acetaminophen (a non-opioid pain reliever) for synergistic pain control.
💊 Composition
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2.5 mg Oxycodone Hydrochloride – a controlled opioid pain reliever that acts on the central nervous system to reduce pain signals.
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300 mg Acetaminophen – a non-opioid analgesic and antipyretic that enhances oxycodone’s effects and helps reduce fever.
This formulation offers effective pain control with reduced opioid exposure, making it ideal for short-term pain management following surgery, dental procedures, or injury recovery.
📌 Key Benefits
💊 Low-dose formulation — effective pain relief with minimized opioid content
🧪 FDA-approved combination therapy for pain management
🛡️ Manufactured by Nesher Pharmaceuticals (a subsidiary of Zydus) – a trusted U.S. drug manufacturer
🔒 Schedule II controlled substance – legal for use only with a valid prescription
✅ Suitable for opioid-naïve patients and short-term pain relief under medical supervision
💊 How to Use PRIMLEV 2.5/300mg
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Typical Dosage: 1 tablet every 6 hours as needed for pain.
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Maximum Daily Dose: Do not exceed 12 tablets per day (3,900 mg acetaminophen maximum).
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Take with food or milk if stomach upset occurs.
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Swallow tablets whole — do not crush, chew, or dissolve.
⚠️ Always follow your prescriber’s directions exactly. Misuse can cause addiction, overdose, or liver damage.
⚠️ Warnings & Precautions
⚠️ High Risk of Misuse and Addiction: PRIMLEV contains oxycodone, a potent opioid.
🚫 Not for use without a doctor’s prescription.
🍷 Avoid alcohol, benzodiazepines, or sedatives while taking PRIMLEV.
🫁 May cause respiratory depression, drowsiness, or dizziness.
👩⚕️ Inform your doctor of any liver disease, substance use disorder, or respiratory conditions before starting therapy.
🚗 Avoid operating machinery or driving until you know how this medication affects you.
🧪 Potential Side Effects
Common (Mild to Moderate):
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Nausea or vomiting
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Constipation
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Drowsiness or dizziness
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Lightheadedness or fatigue
Serious (Seek Immediate Medical Help):
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Slow or difficult breathing
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Signs of liver toxicity (yellowing skin or eyes, dark urine)
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Severe allergic reaction (rash, itching, swelling)
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Confusion, fainting, or irregular heartbeat
If you experience serious symptoms, stop using PRIMLEV and contact a healthcare provider immediately.
📦 Storage & Safe Disposal
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Store at 68°F to 77°F (20°C to 25°C).
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Keep in a locked, child-proof container.
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Do not share your prescription — it’s illegal and unsafe.
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Dispose of unused tablets through a DEA-authorized drug take-back program.
Never flush opioids down the toilet unless specifically directed by the disposal label.
❓ Frequently Asked Questions (FAQs)
Q: What is PRIMLEV 2.5mg/300mg used for?
A: PRIMLEV is used to manage mild to moderate pain requiring an opioid, such as post-surgical or injury-related pain.
Q: Is PRIMLEV the same as Percocet?
A: PRIMLEV is a generic alternative to Percocet with slightly less acetaminophen (300 mg instead of 325 mg), offering similar pain relief.
Q: Can I legally buy PRIMLEV 2.5mg/300mg online in the U.S.?
A: Only through a licensed U.S. pharmacy with a valid prescription. It is a Schedule II controlled substance regulated by the DEA.
Q: Is PRIMLEV safe for long-term use?
A: No. PRIMLEV is intended for short-term use only. Long-term use increases the risk of dependence and liver damage.
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🛒 How to Buy PRIMLEV 2.5mg/300mg Online (U.S. Legal Guidelines)
To order PRIMLEV legally online:
✅ Obtain a prescription from a licensed healthcare provider.
✅ Use only DEA-registered, U.S.-licensed pharmacies.
✅ Ensure the site requires a valid prescription (avoid “no-RX” sites).
✅ Verify HIPAA compliance for personal data protection.
✅ Confirm discreet U.S.-based shipping.
⚠️ Warning: Avoid websites offering PRIMLEV or opioids without a prescription — these are illegal and often sell counterfeit medications that pose serious health risks.
⚖️ Legal Disclaimer
PRIMLEV 2.5mg/300mg (oxycodone HCl and acetaminophen) is a Schedule II controlled substance under U.S. federal law.
Dispensing or purchasing it without a valid prescription is illegal.
Misuse of this medication can lead to addiction, overdose, or death.
Always take only as prescribed, store securely, and dispose of responsibly.




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